The Kannan Lab
Welcome to the Kannan Lab
Cancer treatment resistance is one of the biggest challenges in improving outcomes for patients. We want to understand why some treatments fail and how we can make them work better to help patients. Our lab specifically studies how tumors and their support cells change and adapt during treatment.
We use a combination of advanced techniques, including imaging, 3D cellular models, and computational modeling, to study how tumors stop responding to treatment. If you are a student, researcher, or collaborator passionate about solving this challenge in cancer research, we would love for you to work with us!
News
Nov 2024
Welcome to the lab, Aliakbar Bhaktiari.
Aug 2024
Master student Molly Burke successfully defends her thesis. Congratulations!
June 2024
Master student Lisa Eichhorn successfully defends her thesis. Congratulations!
July 2024
Welcome to the lab, Sania Kheder.
May 2024
Our latest publication on reactivating p53 together with immunotherapy is now out in iScience.
Jan 2024
Welcome to the lab, Lisa Eichhorn and Molly Burke.
March 2023
A huge congratulations to former member, Ada Lerma, on her first-author publication in Scientific Reports! Ada led this work, which describes the efficacy of p53 reactivators in hypoxia.
The team that makes the difference.
Pavitra Kannan, Ph.D.
Principal Investigator
Qi Ying Neo
Ph.D. Student
Improved drug delivery of targeted therapies
Sania Kheder, PharmD
Research Assistant
Efficacy of new therapies in zebrafish models
Aliakbar Bhaktiari
M.Sc. Student
Crosstalk among tumor cells during treatment
Alumni and former students
Marcin Paczkowski
Ph.D. Student -- mathematical models of cellular interactions during radiation
Abul Siddiky
Ph.D. Student -- repurposing chemotherapy drugs to reduce hypoxia
Molly Burke
M.Sc. Student -- deep learning models for vascular segmentation
Lisa Eichhorn
M.Sc. Student -- molecular regulation of p53 signaling in vascular cells
Suzon Fermé
M.Sc. Student -- image analysis of p53 activity in tissues
Omayma Al-Radi
M.Sc. Student -- efficacy of p53 activators in vessels
Paula Lysekär
M.Sc. Student -- imaging p53 responses to hypoxia
Ada Lerma Clavero
M.Sc. Student -- efficacy of p53 activators in hypoxia
Mohamed Ibrahim
B.Sc. Student -- image analysis methods for vessel segmentation
Paula Lysekär
B.Sc. Student -- imaging p53 responses to hypoxia
Pepijn Rakers
B.Sc. Student -- visualizing dynamics of p53 mutations in cells
Ada Lerma Clavero
B.Sc. Student -- efficacy of p53 activators in hypoxia